週次 |
日期 |
單元主題 |
第1週 |
9/18 |
Introduction to structural biology |
第2週 |
9/25 |
New look at the amino acids in structural biological ways. |
第3週 |
10/02 |
The basic blocks of protein structures: Alpha-helix, Beta-sheet, Beta-turns, Beta-bulge, Loops. Available software for PDB file display. |
第4週 |
10/09 |
1. Five basic protein structural domains.
2. Protein functions within cells.
3. Protein physiological functions. |
第5週 |
10/16 |
1. Protein Functional Domain and Classifications.
2. Motif
3. Protein Conformational Changes
|
第6週 |
10/23 |
Introduction to tools for resolving protein structures: An overview. |
第7週 |
10/30 |
Tools for resolving protein structure: X-ray diffraction. |
第8週 |
11/06 |
Mid-term exam: up to Week 6. |
第9週 |
11/13 |
1. Tools for resolving protein structure: CryoEM, NMR and others.
2. 分十組. |
第10週 |
11/20 |
Structural Biology Study Tools:
1. Fluorescence technology for protein motion.
2. Other methods |
第11週 |
11/27 |
BYOC (Bring your own computer) day:
1. PDB Files Format
2. Structure analysis from PDB files
3. Software usage.
4. Bioinformatic analysis. |
第12週 |
12/04 |
Protein quality control, folding and modifications. |
第13週 |
12/11 |
1. Structural biology and cellular biology.
2. Group 1 & 2 presentation |
第14週 |
12/18 |
1. Structural biology & membrane proteins
2. Group 3 & 4 presentation. |
第15週 |
12/25 |
1. Structural biology and Photoreceptors.
2. Group 5 & 6 presentation. |
第16週 |
1/01 |
1. Structural Biology and G proteins.
2. Group 7 & 8 presentation. |
第17週 |
1/08 |
1. Structural Biology and bacterial chemotaxis
2. Group 9 & 10 presentations |